Recent developments in breast cancer research
According to research by Mary Ann Gilligan and published in the American Journal of Public Health women who have surgery for breast cancer in a hospital that has done a lot of them are 20% less likely to die from breast cancer within 5 years
Women who had radiation for breast cancer in the 1970’s and 80’s have a 35-40% greater chance of having heart disease within 20 years. Women who smoked had a even greater risk of heart attack. In addition women who had chemotherapy along with the radiation had a even higher risk of heart disease.
The FDA recently approved the use of GlaxoSmithKline’s Tykerb for women with HER-2 positive advanced breast cancer in combination with the oral chemotherapy drug, Xeloda (capecitabine) who are not responding to Herceptin anymore.
Researchers at the University of British Columbia recently announced in the Public Library of Science the discovery that a protein called podocalyxin changes the shape and adhesive quality of tumor cells. Further research may designing antibodies to block the function of the protein to help fight metastasizing cancer.
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One Response to 'Recent developments in breast cancer research'
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on March 23rd, 2007 at 12:41 am
I love your posts! I am shocked, however, as I search the internet and listen to the media, at how little focus is put on breast cancer PREVENTION. We hear a lot about drugs that may help prevent breast cancer. We know diet, exercise and abstaining from alcohol are important. We hear much about hormone replacement therapy.
A significant amount of research has been conducted on little things that may help. Even things as trivial as sleeping in total darkness. Women that are completely blind have an extremely low rate of breast cancer, whereas women who work nights shifts, or work as flight attendants have an elevated rate. It is felt that melatonin, manufactured by the brain in complete darkness, lowers melatonin levels.
Why are ideas like these, and many more that we found as we researched cancer prevention, never spoken of? I guess I know the answer. There is no money in prevention! Thanks!
Lynne Eldridge M.D.
Author, “Avoiding Cancer One Day At A Time, Practical Advice for Preventing Cancer”
http://www.avoidcancernow.com